Create email templates
If you answer an email to the same question more than once, create an email template so that the next time you are asked the question, you already have an email ready to send.
Back up everything
If you have ever deleted anything accidentally, or suffered a computer crash, you will probably not need to be told about this. Back everything up at least once a day. I use Carbonite, which automatically backs up my whole system every day at 6pm. So, if I lose something or my system dies, I have a copy of everything easily accessible online.
Bookkeeping and invoicing
I would recommend allowing time, twice a month, about two weeks apart, to pay all your bills, input all your expenses, raise all your invoices and check that payments have been made.
For help with managing your workload find out how easy and cost effective it is to delegate some of it to My Virtual Assistant. Download our Information Pack here: http://www.my-va.com